Anti-PKM2 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,ELISA

Purify method:Affinity purified

Species:Human,Mouse,Rat,Monkey

Gene Name:PKM

Synonyms:CTHBP ;Cytosolic thyroid hormone binding protein ;Cytosolic thyroid hormone-binding protein ;KPYM_HUMAN ;MGC3932 ;OIP 3 ;OIP-3 ;OIP3 ;OPA interacting protein 3 ;Opa-interacting protein 3 ;p58 ;PK muscle type ;PK, muscle type ;PK2 ;PK3 ;PKM ;PKM2 ;pykm ;Pyruvate kinase 2/3 ;Pyruvate kinase 3 ;Pyruvate kinase isozymes M1/M2 ;Pyruvate kinase muscle ;Pyruvate kinase muscle isozyme ;pyruvate kinase PKM ;Pyruvate kinase, muscle 2 ;TCB ;THBP1 ;Thyroid hormone binding protein 1 ;Thyroid hormone binding protein cytosolic ;Thyroid hormone-binding protein 1 ;Tumor M2 PK ;Tumor M2-PK .

Gene Synonyms:PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30

Gene Full Name:

Gene Infomation:This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

Antigen:Synthesized peptide derived from the Internal region of human PKM2.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:500-1:2000

Mole Mass:60kDa

Location:Nucleus;

Concentration:1mg/mL

Sequence Similarity:Belongs to the pyruvate kinase family.

Gene Id:5315

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:

Buffer condition:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.