Anti-PP1C Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:IgG2b
Host:Mouse
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:ppp1cc
Synonyms:PP1C;PP-1G;PPP1G.
Gene Synonyms:EC 3.1.3.16;PP 1G;PP-1G;PP1G;PP1G_HUMAN;PP1gamma;PPP 1G;PPP1CC;PPP1CC protein;PPP1G; Protein phosphatase 1 catalytic subunit gamma isoform;Protein phosphatase 1C catalytic subunit;Protein phosphatase 1C subunit;Protein phosphatase 2C gamma isoform; Serine
Gene Full Name:
Gene Infomation:
Antigen:Purified recombinant human PP1C protein fragments expressed in E.coli.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:Human
Reaction:This antibody detects endogenous levels of PP1C and does not cross-react with related proteins.
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:2F2-A3-H10
Dilution:WB 1:500
Mole Mass:38kDa
Location:Cytoplasm.Nucleus.Nucleus ? nucleolus.Nucleus ? nucleoplasm.Nucleus speckle.Chromosome ? centromere ? kinetochore.Cleavage furrow.Midbody.Mitochondrion.
Concentration:
Sequence Similarity:Belongs to the PPP phosphatase family. PP-1 subfamily.
Gene Id:5501
SwissProt ID:P36873
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4 150 mM NaCl)with 0.02% sodium azide 0.1mg/mlBSA and 50% glycerol.
Background:The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.