Anti-PRKAA2 Ascites Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:Unknown
Host:Mouse
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:prkaa2
Synonyms:5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Gene Synonyms:
Gene Full Name:
Gene Infomation:The protein encoded by this gene is a catalytic subunit ofthe AMP-activated protein kinase (AMPK). AMPK is a heterotrimerconsisting of an alpha catalytic subunit, and non-catalytic betaand gamma subunits. AMPK is an important energy-sensing enzyme thatmonitors cellular energy status. In response to cellular metabolicstresses, AMPK is activated, and thus phosphorylates andinactivates acetyl-CoA carboxylase (ACC) and beta-hydroxybeta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved inregulating de novo biosynthesis of fatty acid and cholesterol.Studies of the mouse counterpart suggest that this catalyticsubunit may control whole-body insulin sensitivity and is necessaryfor maintaining myocardial energy homeostasis during ischemia.
Antigen:This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:206CT5.4.2
Dilution:WB::1:1000
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Gene Id:
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Unigene:
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Tissue specificity:
Storage:
Buffer condition:Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.