Anti-Phospho-EGF Receptor (Tyr1068) Rabbit pAb
- 100ug (NP11561) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Phosphoralated
Isotype:Rabbit IgG
Host:Rabbit
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:egfr
Synonyms:ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Gene Synonyms:Avian erythroblastic leukemia viral (v erb b) oncogene homolog;Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;EGFR;EGFR_HUMAN;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog)
Gene Full Name:
Gene Infomation:
Antigen:CDSFLQRp-YSSDPTGA
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500
Mole Mass:175kDa
Location:Cell membrane; Single-pass type I membrane protein_x000D_Endoplasmic reticulum membrane; Single-pass type I membrane protein_x000D_Golgi apparatus membrane; Single-pass type I membrane protein_x000D_Nucleus membrane; Single-pass type I membrane protein_x000D_Endosome_x000D_Endoso
Concentration:
Sequence Similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily._x000D_Contains 1 protein kinase domain.
Gene Id:1956
SwissProt ID:P00533
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:10mM PBS with 0.02% sodium azide 50% glycerol.
Background:EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.