Anti-Phospho-MSK1 (S376) Rabbit pAb
- 100ug (NP21359) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,ICC/IF,IP
Purify method:Affinity Chromatography
Species:Human,Rat
Gene Name:
Synonyms:90 kDa ribosomal protein S6 kinase polypeptide 5; EC 2.7.11.1; KS6A5; MSPK1; Nuclear mitogen- and stress-activated protein kinase-1; RLPK; RPS6KA5; kinase MSK1; ribosomal protein S6 kinase;
Gene Synonyms:
Gene Full Name:
Gene Infomation:Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Antigen:A synthesized peptide derived from human Phospho-MSK1 (S376)
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:Phospho-MSK1 (S376) Antibody detects endogenous levels of Phospho-MSK1 (S376)
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF1:50~1:200 IP 1:50
Mole Mass:90kDa
Location:Membrane > Single-pass type I membrane protein;
Concentration:
Sequence Similarity:Contains 1 VWFA domain.
Gene Id:
SwissProt ID:O75582
Unigene:
Nucleotide Accession:
Tissue specificity:Phospho-MSK1 (S376) Antibody detects endogenous levels of Phospho-MSK1 (S376)
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.