Anti-RAB8A Mouse mAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:

Host:Mouse

Application:WB

Purify method:Affinity purified

Species:Human,Mouse

Gene Name:

Synonyms:Ras-related protein Rab-8A, Oncogene c-mel, RAB8A, MEL, RAB8

Gene Synonyms:

Gene Full Name:

Gene Infomation:The protein encoded by this gene is a member of the RASsuperfamily which are small GTP/GDP-binding proteins with anaverage size of 200 amino acids. The RAS-related proteins of theRAB/YPT family may play a role in the transport of proteins fromthe endoplasmic reticulum to the Golgi and the plasma membrane.This protein shares 97%, 96%, and 51% similarity with the dog RAB8,mouse MEL, and mouse YPT1 proteins, respectively and contains the 4GTP/GDP-binding sites that are present in all the RAS proteins. Theputative effector-binding site of this protein is similar to thatof the RAB/YPT proteins. However, this protein contains aC-terminal CAAX motif that is characteristic of many RASsuperfamily members but which is not found in YPT1 and the majorityof RAB proteins. Although this gene was isolated as a transforminggene from a melanoma cell line, no linkage between MEL andmalignant melanoma has been demonstrable. This oncogene is located800 kb distal to MY09B on chromosome 19p13.1.

Antigen:This RAB8A monoclonal antibody is generated from mouse immunized with RAB8A recombinant protein.

Antigen Synonyms:

Clonality:Monclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:1000

Mole Mass:

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:

Buffer condition:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.