Anti-RB1 Mouse mAb
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Antibody type:Flowcytometry
Label:Unconjugated
Modification:
Isotype:IgG1
Host:Mouse
Application:WB,FC
Purify method:Unpurification
Species:Human
Gene Name:rb1
Synonyms:RB; pRb; OSRC; pp110; p105-Rb
Gene Synonyms:RB; pRb; OSRC; pp110; p105-Rb
Gene Full Name:
Gene Infomation:The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. ;
Antigen:Purified recombinant fragment of human RB1 (AA: 2106-2784) expressed in E. Coli.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:2A11D4
Dilution:
Mole Mass:106.2
Location:
Concentration:
Sequence Similarity:
Gene Id:5925
SwissProt ID:
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:
Buffer condition:Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.