Anti-RTN3 Mouse mAb
- 100ug (NP12506) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:IgG2a
Host:Mouse
Application:ICC
Purify method:Ascitic fluid
Species:Human
Gene Name:RTN3
Synonyms:HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
Gene Synonyms:
Gene Full Name:
Gene Infomation:
Antigen:Purified recombinant fragment of RTN3 expressed in E. Coli.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:1E11
Dilution:WB: N/A; IHC: N/A; ICC: 1/200 - 1/1000; FCM: N/A; Elisa: 1/10000
Mole Mass:113kDa
Location:
Concentration:
Sequence Similarity:
Gene Id:10313
SwissProt ID:O95197
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Ascitic fluid containing 0.03% sodium azide.
Background:RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.