Anti-SCF Rabbit pAb
- 100ug (NP21377) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,ICC/IF,FC
Purify method:Affinity Chromatography
Species:Human
Gene Name:
Synonyms:SF; SCF; MGF; FPH2; KL-1; Kitl;
Gene Synonyms:
Gene Full Name:
Gene Infomation:The epidermal growth factor (EGF) receptor is a 170 kDa transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Activate several signaling cascades to convert extracellular cues into appropriate cellular responses.
Antigen:A synthesized peptide derived from human SCF
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:SCF Antibody detects endogenous levels of SCF
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:2000 IHC 1:50~1:200ICC/IF 1:50~1:200 FC 1:20
Mole Mass:18kDa
Location:Secreted;
Concentration:
Sequence Similarity:Contains 1 protein kinase domain.
Gene Id:
SwissProt ID:P21583
Unigene:
Nucleotide Accession:
Tissue specificity:SCF Antibody detects endogenous levels of SCF
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.