Anti-SEMA4A (N-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human,Mouse

Gene Name:

Synonyms:Semaphorin-4A, Semaphorin-B, Sema B, SEMA4A, SEMAB, SEMB

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a member of the semaphorin family ofsoluble and transmembrane proteins. Semaphorins are involved innumerous functions, including axon guidance, morphogenesis,carcinogenesis, and immunomodulation. The encoded protein is asingle-pass type I membrane protein containing animmunoglobulin-like C2-type domain, a PSI domain and a sema domain.It inhibits axonal extension by providing local signals to specifyterritories inaccessible for growing axons. It is an activator ofT-cell-mediated immunity and suppresses vascular endothelial growthfactor (VEGF)-mediated endothelial cell migration and proliferationin vitro and angiogenesis in vivo. Mutations in this gene areassociated with retinal degenerative diseases including retinitispigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10).Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified.

Antigen:This SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human SEMA4A.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:500

Mole Mass:

Location:

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Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

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Tissue specificity:

Storage:

Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.