Anti-SHANK2 (Center) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Mouse

Gene Name:shank2

Synonyms:SH3 and multiple ankyrin repeat domains protein 2, Shank2, Cortactin-binding protein 1, CortBP1, Proline-rich synapse-associated protein 1, SHANK2, CORTBP1, KIAA1022, PROSAP1

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a protein that is a member of the Shankfamily of synaptic proteins that may function as molecularscaffolds in the postsynaptic density (PSD). Shank proteins containmultiple domains for protein-protein interaction, including ankyrinrepeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alphamotif domain, and a proline-rich region. This particular familymember contains a PDZ domain, a consensus sequence for cortactinSH3 domain-binding peptides and a sterile alpha motif. Thealternative splicing demonstrated in Shank genes has been suggestedas a mechanism for regulating the molecular structure of Shank andthe spectrum of Shank-interacting proteins in the PSDs of adult anddeveloping brain. Two alternative splice variants, encodingdistinct isoforms, are reported. Additional splice variants existbut their full-length nature has not been determined. [provided byRefSeq].

Antigen:This SHANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB31120

Dilution:WB::1:1000

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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.