Anti-SIGLEC5 (N-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:siglec5

Synonyms:Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC5, CD33L2, OBBP2

Gene Synonyms:

Gene Full Name:

Gene Infomation:The sialic acid-binding immunoglobulin-like lectins(SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin(Ig) superfamily that mediate protein-carbohydrate interactions.They specifically interact with sialic acids in glycoproteins andglycolipids, with each SIGLEC having a particular preference forboth the nature of the sialic acid and its glycosidic linkage toadjacent sugars. SIGLECs have similar structures, includingextracellular Ig-like domains composed of an N-terminal V-setdomain followed by varying numbers of C2-set domains. It appearsthat all SIGLECs have an unusual arrangement of conserved cysteineresidues in the V-set and adjacent C2-set domains. Most SIGLECs areexpressed uniquely within the hematopoietic system (Cornish et al.,1998 [PubMed 9731071]).

Antigen:This SIGLEC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the N-terminal region of human SIGLEC5.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB36194

Dilution:WB::1:1000

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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.