Anti-SLC39A7 Rabbit pAb
- 100ug (NP23361) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC
Purify method:Affinity purified
Species:Human,Mouse,Rat
Gene Name:SLC39A7
Synonyms:KE4; HKE4; ZIP7; RING5; H2-KE4; D6S115E; D6S2244E
Gene Synonyms:
Gene Full Name:solute carrier family 39 member 7
Gene Infomation:The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Antigen:Recombinant fusion protein containing a sequence corresponding to amino acids 235-380 of human SLC39A7 (NP_008910.2).
Antigen Synonyms:Zinc transporter SLC39A7
Clonality:Polyclonal antibody
Source:Human
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB1:1000 -1:3000; IHC1:100 -1:200(Optimal dilutions should be determined by the end user)
Mole Mass:50kDa
Location:Endoplasmic reticulum, Golgi apparatus, Membrane
Concentration:
Sequence Similarity:
Gene Id:
SwissProt ID:Q92504
Unigene:7922
Nucleotide Accession:
Tissue specificity:Widely expressed.
Storage:Store at -20°C. Avoid freeze / thaw cycles.
Buffer condition:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:
Molar Function:Zinc transporter, that transports Zn2+ from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca2+, as well as by exogenous Zn2+.
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.