Anti-SPNXB (Center) Rabbit pAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:Rabbit Ig
Host:Rabbit
Application:WB
Purify method:Affinity purified
Species:Human
Gene Name:spnxb
Synonyms:Sperm protein associated with the nucleus on the X chromosome B/F, Cancer/testis antigen 112, CT112, Nuclear-associated protein SPAN-Xb, SPANX-B, Nuclear-associated protein SPAN-Xf, SPANX-F, SPANX family member B/F, SPANXB1, SPANXB
Gene Synonyms:
Gene Full Name:
Gene Infomation:Temporally regulated transcription and translation ofseveral testis-specific genes is required to initiate the series ofmolecular and morphological changes in the male germ cell lineagenecessary for the formation of mature spermatozoa. This gene is amember of the SPANX family of cancer/testis-associated genes, whichare located in a cluster on chromosome X. The SPANX genes encodedifferentially expressed testis-specific proteins that localize tovarious subcellular compartments. This particular gene maps tochromosome X in a head-to-tail orientation with SPANX family memberB1 and appears to be a duplication of that locus. The SPANXB genesare unique members of this gene family, since they contain anadditional 18 nt in their coding region compared to the majority offamily members. Although the protein encoded by this gene containsconsensus nuclear localization signals, the major site forsubcellular localization of expressed protein is in the cytoplasmicdroplets of ejaculated spermatozoa. This protein provides abiochemical marker for studying the unique structures inspermatazoa, while attempting to further define its role inspermatogenesis.
Antigen:This SPNXB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the Central region of human SPNXB.
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:RB42680
Dilution:WB::1:1000
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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.