Anti-STAT1 Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,ICC,IHC

Purify method:Affinity purified

Species:Human

Gene Name:stat1

Synonyms:Signal transducer and activator of transcription 1 91kD ；DKFZp686B04100 ；ISGF 3 ；ISGF-3 ；OTTHUMP00000163552 ；OTTHUMP00000165046 ；OTTHUMP00000165047 ；OTTHUMP00000205845 ；Signal transducer and activator of transcription 1 91kDa ；Signal transducer and activator of transcription 1 alpha/beta ；Signal transducer and activator of transcription 1 ；Signal transducer and activator of transcription 1, 91kD ；Signal transducer and activator of transcription 1-alpha/beta ；Signal Transductor and Activator of Transcription 1 ；STAT 1 ；STAT 91 ；Stat1 ；STAT1_HUMAN ；STAT91 ；Transcription factor ISGF 3 components p91 p84 ；Transcription factor ISGF-3 components p91/p84.

Gene Synonyms:CANDF7; ISGF-3; STAT91

Gene Full Name:

Gene Infomation:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Antigen:The antiserum was produced against synthesized non-phosphopeptide derived from human STAT1 around the phosphorylation site of serine 727.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:

Mole Mass:87

Location:Cytoplasm. Nucleus. Note: Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to IFN-gamma and signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4.

Concentration:

Sequence Similarity:Belongs to the transcription factor STAT family.Contains 1 SH2 domain.

Gene Id:6772

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:STAT1 (Ab-727) antibody detects endogenous levels of total STAT1 protein.

Storage:

Buffer condition:10mM PBS with 0.02% sodium azide, 50% glycerol.

Background:

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.