Anti-SirT2 Mouse mAb
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Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:IgG2b
Host:Mouse
Application:WB,IF
Purify method:Affinity purified
Species:Human,Mouse,Rat
Gene Name:sirt2
Synonyms:SIR2; SIR2L; SIR2L2.
Gene Synonyms:FLJ35621;FLJ37491;NAD dependent deacetylase sirtuin 2;NAD-dependent deacetylase sirtuin-2;NAD-dependent protein deacetylase sirtuin-2;Regulatory protein SIR2 homolog 2;Silencing information regulator 2 like;Silent information regulator 2;Silent mating typ
Gene Full Name:
Gene Infomation:
Antigen:Purified recombinant human SirT2 protein expressed in E.coli.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:Human
Reaction:This antibody detects endogenous levels of SirT2 and does not cross-react with related proteins.
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:1D4-H11-H11
Dilution:WB 1:1000
Mole Mass:43kDa
Location:Nucleus.
Concentration:2.22mg/ml
Sequence Similarity:Belongs to the sirtuin family._x000D_Contains 1 deacetylase sirtuin-type domain.
Gene Id:22933
SwissProt ID:Q8IXJ6
Unigene:
Nucleotide Accession:
Tissue specificity:
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Background:Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.