Anti-TGFB2 Mouse mAb
- 100ug (NP25884) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:
Isotype:
Host:Mouse
Application:WB,IHC-P,IF
Purify method:Affinity purified
Species:Human
Gene Name:
Synonyms:Transforming growth factor beta-2, TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP, TGFB2
Gene Synonyms:
Gene Full Name:
Gene Infomation:This gene encodes a member of the transforming growthfactor beta (TGFB) family of cytokines, which are multifunctionalpeptides that regulate proliferation, differentiation, adhesion,migration, and other functions in many cell types by transducingtheir signal through combinations of transmembrane type I and typeII receptors (TGFBR1 and TGFBR2) and their downstream effectors,the SMAD proteins. Disruption of the TGFB/SMAD pathway has beenimplicated in a variety of human cancers. The encoded protein issecreted and has suppressive effects of interleukin-2 dependentT-cell growth. Translocation t(1;7)(q41;p21) between this gene andHDAC9 is associated with Peters' anomaly, a congenital defect ofthe anterior chamber of the eye. The knockout mice lacking thisgene show perinatal mortality and a wide range of developmental,including cardiac, defects. Alternatively spliced transcriptvariants encoding different isoforms have been identified.
Antigen:This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.
Antigen Synonyms:
Clonality:Monclonal antibody
Source:HUMAN
Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB::1:500-1:1000ICC::1:10~50IHC::1:10~50
Mole Mass:
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Gene Id:
SwissProt ID:
Unigene:
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Storage:
Buffer condition:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Background:
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.