Anti-XPC (N-term) Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:Rabbit Ig

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human

Gene Name:xpc

Synonyms:DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125, XPC, XPCC

Gene Synonyms:

Gene Full Name:

Gene Infomation:This gene encodes a component of the nucleotide excisionrepair (NER) pathway. There are multiple components involved in theNER pathway, including Xeroderma pigmentosum (XP) A-G and V,Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) groupA, etc. This component, XPC, plays an important role in the earlysteps of global genome NER, especially in damage recognition, opencomplex formation, and repair protein complex formation. Mutationsin this gene or some other NER components result in Xerodermapigmentosum, a rare autosomal recessive disorder characterized byincreased sensitivity to sunlight with the development ofcarcinomas at an early age. Alternatively spliced transcriptvariants have been found for this gene.

Antigen:This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:HUMAN

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:RB40964

Dilution:WB::1:2000

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Buffer condition:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Background:

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Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.