Anti-c-Raf Rabbit pAb

Antibody type:Primary antibody

Label:Unconjugated

Modification:Unmodification

Isotype:Rabbit IgG

Host:Rabbit

Application:WB

Purify method:Affinity purified

Species:Human,Mouse

Gene Name:c-raf/raf-1

Synonyms:NS5; CRAF; Raf-1; c-Raf; CMD1NN

Gene Synonyms:c Raf;C-raf;C-Raf proto-oncogene, serine/threonine kinase;CMD1NN;Craf 1 transforming gene;cRaf;Craf1 transforming gene;EC 2.7.11.1;kinase Raf1;Murine sarcoma 3611 oncogene 1;NS5;Oncogene MIL;Oncogene RAF1;OTTHUMP00000160218;OTTHUMP00000207813;OTTHUMP00000

Gene Full Name:

Gene Infomation:

Antigen:QRQRSTSTPNVHMC

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:

Reaction:

Form:Liquid

Tested Applications:

• Western blot (1:100 to 1:500)
• Immunofluorescence (1:50 to 1:400)
• Immunohistochemistry (1:200 to 1:500)
• Flow cytometry analysis (1:200 to 1:500)
• Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB 1:1000

Mole Mass:75kDa

Location:Cytoplasm_x000D_Cell membrane_x000D_Mitochondrion_x000D_Nucleus

Concentration:

Sequence Similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily._x000D_Contains 1 phorbol-ester/DAG-type zinc finger._x000D_Contains 1 protein kinase domain._x000D_Contains 1 RBD (Ras-binding) domain.

Gene Id:5894

SwissProt ID:P04049

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Buffer condition:10mM PBS with 0.02% sodium azide 50% glycerol.

Background:Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

Molar Function:

Western Blot: 

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.