Anti-eIF2α Rabbit pAb

100ug (NP13721) Please inquiry

Antibody type:Primary antibody

Label:Unconjugated

Modification:

Isotype:IgG

Host:Rabbit

Application:WB,IHC,ELISA

Purify method:Affinity purified

Species:Human,Mouse,Rat,Monkey

Gene Name:EIF2S1

Synonyms:Dmel\CG6376 ;Dmel_CG6376 ;drosE2F1 ;E(Sev-CycE)3A ;E(var)3-93E ;E2-promoter binding facto ;E2F 1 ;E2F transcription factor 1 ;E2F-1 ;E2f-PA ;E2f-PB ;E2f-PC ;E2F1 ;E2f1 E2F transcription factor 1 ;E2F1_HUMAN ;Evar(3)164 ;KIAA4009 ;l(3)07172 ;l(3)j3B1 ;l(3)j3C2 ;l(3)rM729 ;mKIAA4009 ;OTTHUMP00000030661 ;PBR3 ;PRB binding protein E2F 1 ;PRB-binding protein E2F-1 ;RBAP 1 ;RBAP-1 ;RBAP1 ;RBBP-3 ;RBBP3 ;RBP 3 ;RBP3 ;Retinoblastoma-associated protein 1 ;Retinoblastoma-binding protein 3 ;Transcription factor E2F1.

Gene Synonyms:EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha

Gene Full Name:

Gene Infomation:The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]

Antigen:Synthesized peptide derived from eIF2α . at AA range: 30-110.

Antigen Synonyms:

Clonality:Polyclonal antibody

Source:Human

Reaction:

Form:Liquid

Tested Applications:

Western blot (1:100 to 1:500)
Immunofluorescence (1:50 to 1:400)
Immunohistochemistry (1:200 to 1:500)
Flow cytometry analysis (1:200 to 1:500)
Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:

Dilution:WB::1:500-1:2000IHC::1:100-1:300

Mole Mass:38kDa

Location:Cytoplasmic granule;

Concentration:1mg/mL

Sequence Similarity:Contains 1 S1 motif domain.

Gene Id:1965

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:

Buffer condition:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Background:

Molar Function:

Western Blot:

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.