Anti-p73 Rabbit pAb
- 100ug (NP21641) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,ICC/IF
Purify method:Affinity Chromatography
Species:Human,Mouse,Rat
Gene Name:
Synonyms:p53-like transcription factor; p53-related protein; P73 alpha protein; p73-alpha; TP73; TRP73; Tumor protein p73;
Gene Synonyms:
Gene Full Name:
Gene Infomation:ERK1 p42 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters.ERK2 p44 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
Antigen:A synthesized peptide derived from human p73
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:p73 Antibody detects endogenous levels of p73
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Mole Mass:70kDa
Location:Nucleus;
Concentration:
Sequence Similarity:Contains 1 protein kinase domain.
Gene Id:
SwissProt ID:O15350
Unigene:
Nucleotide Accession:
Tissue specificity:p73 Antibody detects endogenous levels of p73
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.