Anti-pro Caspase 9 Rabbit pAb
- 100ug (NP21275) Please inquiry
Antibody type:Primary antibody
Label:Unconjugated
Modification:Unmodification
Isotype:Rabbit IgG
Host:Rabbit
Application:WB,IHC,FC
Purify method:Affinity Chromatography
Species:Human
Gene Name:
Synonyms:APAF-3; APAF3; Apoptotic protease Mch-6; ICE-LAP6; Apoptotic protease-activating factor 3; CASP-9; CASP9; Caspase-9 subunit p10; ICE-like apoptotic protease 6; ICELAP6; MCH6;
Gene Synonyms:
Gene Full Name:
Gene Infomation:Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
Antigen:A synthesized peptide derived from human pro Caspase 9
Antigen Synonyms:
Clonality:Polyclonal antibody
Source:
Reaction:pro Caspase 9 Antibody detects endogenous levels of pro Caspase 9
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:
Dilution:WB 1:500~1:2000 IHC 1:50~1:200 FC 1:50
Mole Mass:46kDa
Location:
Concentration:
Sequence Similarity:Contains 1 protein kinase domain.
Gene Id:
SwissProt ID:P55211
Unigene:
Nucleotide Accession:
Tissue specificity:pro Caspase 9 Antibody detects endogenous levels of pro Caspase 9
Storage:Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Buffer condition:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background:Caspases are a family of cytosolic aspartate specific cysteine proteases. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis.
Molar Function:
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.