Cynomolgus IFNA13 / Interferon alpha-13 Protein (Fc Tag)

IFNA13

Catalog Number	P90108-C02H
Organism Species	Cynomolgus
Host	Human Cells
Synonyms	IFNA13
Molecular Weight	The recombinant cynomolgus IFNA13 is a disulfide-linked homodimer. The reduced monomer comprises 407 amino acids and has a calculated molecular mass of 46.4 KDa.The apparent molecular mass of the protein is approximately 47 KDa respectively in SDS-PAGE.
predicted N	Cys 25
SDS-PAGE
Purity	> 85 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the cynomolgus IFNA13 (G7NFW4) (Met1-Glu190) was expressed with the Fc region of human IgG1 at the C-terminus.
Bio-activity	Measured in antiviral assay using WISH human amnion cells infected with vesicular stomatitisvirus (VSV). The ED₅₀ for this effect is typically 0.5-3 ng/mL.
Research Area	Cardiovascular \|Angiogenesis \|Cytokines / Chemokines in Angiogenesis \|Interferons
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Mahmutovic S, et al.. (2004) Significance of the interferon (IFN) in the therapy. Bosn J Basic Med Sci. 4(4): 42-4. Wang, et al.. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12.