Cynomolgus TALLA-1 / TSPAN7 Protein (Fc Tag)
TSPAN7
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Catalog Number | P90243-C04H |
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Organism Species | Cynomolgus |
Host | Human Cells |
Synonyms | TSPAN7 |
Molecular Weight | The recombinant cynomolgus TSPAN7 is a disulfide-linked homodimer. The reduced monomer comprises 337 amino acids and has a calculated molecular mass of 38.2 KDa. The apparent molecular mass of it is approximately 45-49 KDa respectively in SDS-PAGE. |
predicted N | Asp |
SDS-PAGE | |
Purity | (92.7 %+5.7) % as determined by SDS-PAGE |
Protein Construction | A DNA sequence encoding the cynomolgus TSPAN7 (Q4R5A3) (Arg113-Met213) was expressed with the Fc region of mouse IgG1 at the N-terminus. |
Bio-activity | |
Research Area | Signaling |Signal Transduction |Metabolism |Pathways and Processes |Metabolic signaling pathways |Amino acid metabolism | |
Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Background | TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. |
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