Human AARSD1 Protein (His Tag)
AARSD1
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| Catalog Number | P14280-H07E |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | AARSD1 |
| Molecular Weight | The recombinant human AARSD1 comprises 365 amino acids and has a predicted molecular mass of 40.5 kDa. The apparent molecular mass of the protein is approximately 40 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| predicted N | His |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human AARSD1 (Q9BTE6-2) (Thr176-Glu525) was expressed with a polyhistidine tag at the N-terminus. |
| Bio-activity | |
| Research Area | Epigenetics |DNA / RNA |Translation |tRNA synthetase |
| Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcript variants have been described for AARSD1: NM_025267.3, NM_001136042.2, NM_001142653.1 and NM_001142654.1. It has been determined that the latter two variants represent a distinct upstream locus, which is now represented by GeneID:100885848 (PTGES3L), while the former two variants represent readthrough transcripts between PTGES3L and this locus (AARSD1). The readthrough locus (PTGES3L-AARSD1) is now represented by GeneID:100885850. |
| Reference |