Human ARF3 / ADP-ribosylation factor 3 Protein (His Tag)
ARF3
- 100ug (NPP1906) Please inquiry
| Catalog Number | P14967-H07E |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | ARF3 |
| Molecular Weight | The recombinant human ARF3 consists of 196 amino acids and predicts a molecular mass of 22.4 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | His |
| SDS-PAGE |  |
| Purity | > 85 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human ARF3 (P61204) (Met1-Lys181) was expressed with a polyhistidine tag at the N-terminus. |
| Bio-activity | |
| Research Area | Immunology |Signal Transduction |Protein Trafficking |Golgi Proteins |
| Formulation | Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | ARF3, also known as ADP-ribosylation factor 3, belongs to the RAS superfamily. Members of this family include ARF1, ARF2, ARF3, ARF4, ARF5 and ARF6. ARF3 gene is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF3 functions as an allosteric activator of the cholera toxin subunit, an ADP-ribosyltransferase. It is involved in protein trafficking and may modulate vesicle budding and uncoating within the Golgi apparatus. |
| Reference |