Human ART3 Protein (His Tag)
ARTC3
- 100ug (NPP1910) Please inquiry
| Catalog Number | P13542-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | ARTC3 |
| Molecular Weight | The recombinant human ART3 consists of 347 amino acids and predicts a molecular mass of 39.6 KDa. It migrates as an approximately 49 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Glu 27 |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human ART3(AAH08397.1) (Met1-Ser362) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | ART3 is an arginine-specific ADP-ribosyltransferase which belongs to the Arg-specific ADP-ribosyltransferase family. ART3 catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. It is expressed specifically in testis. ART3 pseudogene is located on chromosome 11. ART3 was identified as a susceptibility gene for non-obstructive azoospermia (NOA). It is a novel therapeutic target in the treatment of NOA. |
| Reference |