Human BLBP / FABP7 Protein
B-FABP,BLBP,FABPB,LTR2-FABP7,MRG
- 100ug (NPP1928) Please inquiry
| Catalog Number | P12577-HNAE |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | B-FABP,BLBP,FABPB,LTR2-FABP7,MRG |
| Molecular Weight | The recombinant human FABP7 consists of 132 amino acids and predicts a molecular mass of 14.9 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Met |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the mature form of human FABP7 (O15540) (Met1-Ala132) was expressed. |
| Bio-activity | |
| Research Area | Signaling |Signal Transduction |Metabolism |Types of disease |Metabolism in Cancer |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives. |
| Reference |