Human CCDC47 Protein(His Tag)
GK001,MSTP041
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| Catalog Number | P13274-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | GK001,MSTP041 |
| Molecular Weight | The recombinant human CCDC47 consists of 126 amino acids and predicts a molecular mass of 14.7 KDa. It migrates as an approximately 22 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Lys 21 |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human CCDC47 (Q96A33-1) (Met1-Ser135) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | CCDC47 gene is expressed at high level. The gene contains 16 distinct gt-ag introns. Transcription produces 9 different mRNAs, 6 alternatively spliced variants and 3 unspliced forms. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 8 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries. Functionally, CCDC47 gene has been proposed to participate in processes such as calcium ion homeostasis, embryo development, ER overload response and post-embryonic development. CCDC47 are expected to have molecular function (calcium ion binding) and to localize in various compartments (membrane, endoplasmic reticulum, integral to membrane, microsome). |
| Reference |