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Human CD16b / FCGR3B Protein

CD16,CD16b,Fc gamma RIIIb,FCG3,FCGR3,FCR-10,FCRIII,FCRIIIb

Catalog Number P11046-HNAE
Organism Species Human
Host E. coli
Synonyms CD16,CD16b,Fc gamma RIIIb,FCG3,FCGR3,FCR-10,FCRIII,FCRIIIb
Molecular Weight The recombinant human CD16b comprises 176 amino acids and has a predicted molecular mass of 20 kDa. It migrates as an approximately 22 kDa band in SDS-PAGE under reducing conditions.
predicted N Met
SDS-PAGE
Purity > 95 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the mature form of human CD16b (O75015-1) (Met 18-Gly 193) was expressed and purified.
Bio-activity Using the Octet RED System, the affinity constant (Kd) of CD16b bound to Human IgG1 was 80nM.
Research Area Immunology |Innate Immunity |Monocytes/Macrophages |Monocyte Markers
Formulation Lyophilized from sterile 20mM Tris, 50mM NaCl, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference