Human CFHR2 / FHR2 / HFL3 Protein (His Tag)
CFHL2,FHR2,HFL3
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| Catalog Number | P13920-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | CFHL2,FHR2,HFL3 |
| Molecular Weight | The recombinant human CFHR2 consists of 263 amino acids and predicts a molecular mass of 30.2 KDa. It migrates as an approximately 31 and 35 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Glu 19 |
| SDS-PAGE |  |
| Purity | > (46.1+45.6) % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human CFHR2 (P36980-1) (Met1-Lys270) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Signaling |Signal Transduction |Metabolism |Types of disease |Metabolism in Cancer |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. CFHR2 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. |
| Reference |