Human CNPY2 Protein (His Tag)
HP10390,MSAP,TMEM4,ZSIG9
- 100ug (NPP2033) Please inquiry
| Catalog Number | P13771-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | HP10390,MSAP,TMEM4,ZSIG9 |
| Molecular Weight | The recombinant human CNPY2 consists of 173 amino acids and predicts a molecular mass of 20 KDa. It migrates as an approximately 20 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Arg 21 |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human CNPY2 (Q9Y2B0-1) (Met1-Ser178) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Cancer |Signal transduction |Metabolism |Mitochondrial |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. It is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. Downregulation of CNPY2 by RNA interference significantly decreased glioma cell migration and phosphorylation of MRLC. Inhibition of the corresponding MRLC kinase by ML-7 did not affect migration of CNPY2-overexpressing cells. |
| Reference |