Human Cytoglobin / CYGB Protein (His Tag)
HGB,STAP
- 100ug (NPP2068) Please inquiry
| Catalog Number | P14367-H07E |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | HGB,STAP |
| Molecular Weight | The recombinant human CYGB consists of 205 amino acids and predicts a molecular mass of 23.2 KDa. It migrates as an approximately 26 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | His |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human CYGB (AAH29798.1) (Met1-Pro190) was expressed with a polyhistidine tag at the N-terminus. |
| Bio-activity | |
| Research Area | Immunology |Signal Transduction |Protein Trafficking |Vesicle Transport |Regulation |
| Formulation | Lyophilized from sterile 20mM Tris, 100mM NaCl, 10% Glycerol, pH 8.0. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | Cytoglobin, also known as CYGB, is a globin molecule ubiquitously expressed in all tissues and most notably utilized in marine mammals. Its avtual function is still unknown. It is thought to be a method of protection under conditions of hypoxia. The predicted function of cytoglobin is the transfer of oxygen from arterial blood to the brain. Cytoglobin is also present in chondroblasts and osteoblasts and shows a decreased level of expression upon differentiation to chondrocytes and osteocytes. Cytoglobin may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or reactive oxygen species, or serve a protective function during oxidative stress. |
| Reference |