Human DCBLD2 / ESDN / CLCP1 Protein (His Tag)
CLCP1,ESDN
- 100ug (NPP2074) Please inquiry
| Catalog Number | P13615-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | CLCP1,ESDN |
| Molecular Weight | The recombinant human DCBLD2 consists of 473 amino acids and predicts a molecular mass of 52.6 KDa. It migrates as an approximately 69-89 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Gln 21 |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human DCBLD2 (NP_563615.3) (Met1-Ala482) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on. |
| Reference |