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Human EPDR1 Protein (His Tag)

EPDR,MERP-1,MERP1,UCC1

Catalog Number P13665-H08H
Organism Species Human
Host Human Cells
Synonyms EPDR,MERP-1,MERP1,UCC1
Molecular Weight The recombinant human EPDR1 comprises 198 amino acids and has a predicted molecular mass of 23.2 kDa. The apparent molecular mass of the protein is approximately 31 and 34 kDa in SDS-PAGE under reducing conditions
predicted N Ala 38
SDS-PAGE
Purity (23.6+72.7) % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the human EPDR1 (Q9UM22-1) (Met1-Trp224) with a C-terminal polyhistidine tag was expressed.
Bio-activity
Research Area Neuroscience |Cell Type Marker in Neurodevelopment |Neuronal Cell Markers |Synapse & Synaptic Proteins |Calcium Signaling |Calcium Binding Proteins |
Formulation Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background EPDR1 is a member of the ependymin family. EPDR1 is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. It may play a role in calcium-dependent cell adhesion. EPDR1 is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
Reference
  • Suga T. et al., 2008, Int J Radiat Oncol Biol Phys. 72 (3): 808-13.
  • Rose JE. et al., 2010, Mol Med. 16 (7-8): 247-53.
  • Cheng W. et al., 2010, J Huazhong Univ Sci Technolog Med Sci. 30 (3): 391-6.