Human FABP6 / I-BABP Protein
I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP
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| Catalog Number | P12579-HNAE |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP |
| Molecular Weight | The recombinant human FABP6 consisting of 128 amino acids and has a calculated molecular mass of 14.4 kDa as estimated in SDS-PAGE under reducing conditions. |
| predicted N | Met 1 |
| SDS-PAGE |  |
| Purity | > 98 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human FABP6 (AAH22489.1) (Met 1-Ala 128) was expressed and purified. |
| Bio-activity | |
| Research Area | Cancer |Cancer Metabolism |Metabolic signaling |Metabolism of lipids and lipoprotein |
| Formulation | Lyophilized from sterile PBS, pH 7.5 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. FABP6 / I-BABP is a cancer-related protein that acts as an intracellular transporter of bile acid in the ileal epithelium. FABP6 / I-BABP may also play an important role in early carcinogenesis. |
| Reference |