Human FKBP3 / FKBP25 Protein (GST Tag)

FKBP-25,FKBP-3,FKBP25,PPIase

Catalog Number	P12582-H09E
Organism Species	Human
Host	E. coli
Synonyms	FKBP-25,FKBP-3,FKBP25,PPIase
Molecular Weight	The recombinant human FKBP3/GST chimera consists of 455 amino acids and has a predicted molecular mass of 52 kDa. It migrates as an approxiamtely 48 kDa band in SDS-PAGE under reducing conditions.
predicted N	Met
SDS-PAGE
Purity	> 90 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human FKBP3 (Q00688) (Ala 2-Asp 224) was fused with the GST tag at the N-terminus.
Bio-activity
Research Area	Cancer \|Signal transduction \|Metabolism \|Pathways and Processes \|Co-factors
Formulation	Lyophilized from sterile 50mM tris, 0.15M NaCl, 0.5mM GSH, pH 8.0 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Wiederrecht G., et al., 1992, Biochem. Biophys. Res. Commun. 185: 298 - 303. Dephoure N., et al.,2008, Proc. Natl. Acad. Sci. USA.105:10762-7. Gauci S., et al., 2009, Anal. Chem. 81:4493-4501. Choudhary C., et al., 2009, Science. 325:834-840.