Human GPR56 / TM7LN4 Protein (His Tag)

BFPP,DKFZp781L1398,TM7LN4,TM7XN1,UNQ540/PRO1083

Catalog Number	P11017-H08H
Organism Species	Human
Host	Human Cells
Synonyms	BFPP,DKFZp781L1398,TM7LN4,TM7XN1,UNQ540/PRO1083
Molecular Weight	The secreted recombinant human GPR56 comprises 328 amino acids and has a predicted molecular mass of 37.4 kDa. As a result of glycosylation, the apparent molecular mass of rhGPR56 is approximately 50-60 kDa in SDS-PAGE under reducing conditions.
predicted N	Arg 26
SDS-PAGE
Purity	> 80 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human GPR56 isoform b (NP_958933.1) extracellular domain (Met 1-Val 342) was fused with a polyhistidine tag at the C-terminus.
Bio-activity
Research Area	Immunology \|Signal Transduction \|Signaling Pathway \|G Protein Signaling \|G Protein-Coupled Receptors (GPCRs) \|Adhesion G Protein-Coupled Receptors \|
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Liu M., et al., 1999, Genomics 55: 296-305. Huang,Y. et al., 2008, Mol Cell Biochem. 308 (1-2):133-9. Li,S. et al., 2008, J Neurosci 28 (22):5817-26. Jin,Z. et al., 2009, Prog Mol Biol Transl Sci. 89 :1-13. Xu,L. et al., 2010, Clin Exp Metastasis. 27 (4):241-9.