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Human IL36G / IL1F9 Protein (aa 18-169)

IL-1F9,IL-1H1,IL-1RP2,IL1E,IL1F9,IL1H1,IL1RP2

Catalog Number P10124-HNCE1
Organism Species Human
Host E. coli
Synonyms IL-1F9,IL-1H1,IL-1RP2,IL1E,IL1F9,IL1H1,IL1RP2
Molecular Weight The recombinant human IL1F9 consists of 154 amino acids and predicts a molecular mass of 17 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.
predicted N Gly
SDS-PAGE
Purity > 96 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the human IL1F9 (NP_062564) (Ser18-Asp169) was expressed and purified, with two additional amino acids (Gly & Pro) at the N-terminus.
Bio-activity
Research Area Cardiovascular |Angiogenesis |Cytokines / Chemokines in Angiogenesis |Interleukins
Formulation Lyophilized from sterile PBS pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference
  • Dinarello CA. (2002) The IL-1 family and inflammatory diseases. Clin Exp Rheumatol. 20(5): 1-13.
  • Berglof E, et al. (2003) IL-1Rrp2 expression and IL-1F9 (IL-1H1) actions in brain cells. J Neuroimmunol. 139(1-2): 36-43.
  • Dunn E, et al. (2001) Annotating genes with potential roles in the immune system: six new members of the IL-1 family. Trends Immunol.22(10): 533-6.
  • Towne JE, et al. (2004) Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs. J Biol Chem. 279(14): 13677-88.