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Human IgG2-Fc Protein (257 Ser/Ala)

IgG2

Catalog Number P13504-HNAH
Organism Species Human
Host Human Cells
Synonyms IgG2
Molecular Weight The recombinant human IgG2-Fc consists of 228 amino acids and has a predicted molecular mass of 25 kDa. As a result of glycosylation, the apparent molecular mass of IgG2-Fc is approximately 34 kDa in SDS-PAGE under reducing conditions.
predicted N Glu 99
SDS-PAGE
Purity > 90 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the human IgG2 Fc region (P01859) (Glu 99-Lys 327, 257Ser/Ala) was expressed and purified.
Bio-activity Measured by its ability to bind human CD32a-His (P10374-H08H1) in a functional ELISA.
Research Area
Formulation Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference