Human Interferon alpha 2 / IFNA2 Protein

IFN-alphaA,IFNA,IFNA2B,IFNAB,INFA2,Interferon alpha 2

Catalog Number	P13833-HNAY
Organism Species	Human
Host	Yeast
Synonyms	IFN-alphaA,IFNA,IFNA2B,IFNAB,INFA2,Interferon alpha 2
Molecular Weight	The recombinant human IFNA2 consists 165 amino acids and predicts a molecular mass of 19.3 kDa.
predicted N	Cys 24
SDS-PAGE
Purity	> 95 % as determined by SDS-PAGE.
Protein Construction	A DNA sequence encoding the human IFNA2 (NP_000596.2) (Cys24-Glu188) was expressed.
Bio-activity
Research Area	Immunology \|Cytokines & Growth Factors \|Cytokine & Receptor \|Interferon & Receptor \|Interferon
Formulation	Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Wang, et al. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12. Groopman JE, et al. (1984) Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med. 100(5): 671-6. Krueger JM, et al. (1987) Interferon alpha-2 enhances slow-wave sleep in rabbits. Int J Immunopharmacol. 9(1): 23-30.