Human LC3B / MAP1LC3B Protein (His Tag)
ATG8F,LC3B,MAP1A/1BLC3,MAP1LC3B-a
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| Catalog Number | P14555-H07E |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | ATG8F,LC3B,MAP1A/1BLC3,MAP1LC3B-a |
| Molecular Weight | The recombinant human MAP1LC3B consists of 140 amino acids and predicts a molecular mass of 16.5 KDa. It migrates as an approximately 17 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | His |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human MAP1LC3B (Q9GZQ8) (Met1-Val125) was expressed with a polyhistidine tag at the N-terminus. |
| Bio-activity | |
| Research Area | Cardiovascular |Heart |Autophagy |Autophagosome |
| Formulation | Lyophilized from sterile PBS, 20% glycerol, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | LC3B, also known as MAP1LC3B, is a member of the MAP1 LC3 family. It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. LC3B also plays a role in autophagy, a process that involves the bulk degradation of cytoplasmic component. |
| Reference |