Human LILRA5 Protein (Fc Tag)
CD85,CD85F,ILT-11,ILT11,LILRB7,LIR-9,LIR9
- 100ug (NPP2225) Please inquiry
| Catalog Number | P16059-H02H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | CD85,CD85F,ILT-11,ILT11,LILRB7,LIR-9,LIR9 |
| Molecular Weight | The recombinant human LILRA5 consists 465 amino acids and predicts a molecular mass of 52 kDa. |
| predicted N | Gly 42 |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE. |
| Protein Construction | A DNA sequence encoding the human LILRA5 (NP_067073.1) (Met1-Arg268) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Bio-activity | |
| Research Area | Immunology |Signal Transduction |ITIM/ITAM Immunoreceptors and Related Molecules |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. |
| Reference |