Human LMAN2L Protein (His Tag)
VIPL
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| Catalog Number | P13822-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | VIPL |
| Molecular Weight | The recombinant human LMAN2L consists of 271 amino acids and predicts a molecular mass of 31.4 KDa. It migrates as an approximately 32 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Gly 45 |
| SDS-PAGE |  |
| Purity | > 85 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human LMAN2L (Q9H0V9-1) (Met1-Ala304) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Signaling |Signal Transduction |Protein Trafficking |Golgi Proteins |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | LMAN2L contains 1 L-type lectin-like domain and is expressed in numerous tissues. It is highly expressed in skeletal muscle and kidney, and its intermediate expression levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. LMAN2L may be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. It also may function as a regulator of ERGIC-53. LMAN2L gene may be modulated by acetylation; phosphorylation, as detailed at PhosphoSite. Alternative splicing produces 2 isoforms of the human protein. LMAN2L localize in various compartments. |
| Reference |