Human MRTO4 / MRT4 Protein (His Tag)

C1orf33,dJ657E11.4,MRT4

Catalog Number	P14639-H07E
Organism Species	Human
Host	E. coli
Synonyms	C1orf33,dJ657E11.4,MRT4
Molecular Weight	The recombinant human MRTO4 consists of 254 amino acids and predicts a molecular mass of 29.4 KDa. It migrates as an approximately 32 KDa band in SDS-PAGE under reducing conditions.
predicted N	His
SDS-PAGE
Purity	> 95 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human MRTO4 (Q9UKD2) (Met1-Asp239) was expressed with a polyhistidine tag at the N-terminus.
Bio-activity
Research Area	Epigenetics \|DNA / RNA \|RNA Processing \|Other in RNA processing
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background	MRTO4, also known as MRT4, belongs to the ribosomal protein L10P family. MRTO4 is a ribosomal P0-like protein showing extensive sequence similarity to the ribosomal P0 protein. The precise function of MRTO4 is currently unknown. It appears to be involved in mRNA turnover and ribosome assembly. MRTO4 acts as a trans-acting factor which modulates the assembly of the pre-60S particle.
Reference	Zhao J. et al., 2011, J Proteomics. 75 (2): 588-602. Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81. Wu Z. et al., 2012, PLoS One. 7 (8): e43997. Michalec B. et al., 2010, Int J Biochem Cell Biol. 42 (5): 736-48.