Human NELL2 Protein (His Tag)

NRP2

Catalog Number	P13132-H08B
Organism Species	Human
Host	Baculovirus-Insect Cells
Synonyms	NRP2
Molecular Weight	The secreted recombinant human NELL2 consists of 805 amino acids and predicts a molecular mass of 90.4 kDa. It migrates as an approximately 110 KDa band in SDS-PAGE under reducing conditions.
predicted N	Leu 22
SDS-PAGE
Purity	> 87 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human NELL2 (Q99435) (Met 1-Leu 816) was fused with a polyhistidine tag at the C-terminus.
Bio-activity
Research Area	Epigenetics \|Cell cycle \|DNA Damage & Repair \|Homologous Recombination (HR)
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Kuroda S, et al. (1999) Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2. Biochem Biophys Res Commun. 265(1): 79-86. Oyasu M, et al. (2000) Immunocytochemical localization of a neuron-specific thrombospondin-1-like protein, NELL2: light and electron microscopic studies in the rat brain. Brain Res Mol Brain Res. 76(1): 151-60. Nelson BR, et al. (2002) Restricted neural epidermal growth factor-like like 2 (NELL2) expression during muscle and neuronal differentiation. Mech Dev. 119 Suppl 1: 11-9.