Human PNLIPRP1 / PLRP1 Protein (His Tag)
PLRP1
- 100ug (NPP2418) Please inquiry
| Catalog Number | P13565-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | PLRP1 |
| Molecular Weight | The recombinant human PNLIPRP1 comprises 461 amino acids and has a predicted molecular mass of 51.4 kDa. The apparent molecular mass of the protein is approximately 44-48 kDa in SDS-PAGE under reducing conditions. |
| predicted N | Lys 18 |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human PNLIPRP1 (AAH25784.1) (Met1-Cys467) was expressed with a C-terminal polyhistidine tag. |
| Bio-activity | |
| Research Area | Signaling |Signal Transduction |Metabolism |Types of disease |Metabolism in Cancer |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | PNLIPRP1, also known as PLRP1, belongs to the AB hydrolase superfamily, Lipase family. PNLIPRP1 is structurally similar to PLRP2. However, these two proteins display different functional properties. PNLIPRP1 may function as inhibitor of dietary triglyceride digestion. It lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters. PLRP2 hydrolyses milk fat with a lower catalytic efficiency than that of PL. PLRP2 activity, higher on homogenized than on native milk fat, is differently influenced by fatty acids and colipase depending on a proteolytic cleavage in the lid domain. |
| Reference |