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Human Peroxiredoxin 2 / PRDX2 Protein (His Tag)

HEL-S-2a,NKEF-B,NKEFB,PRP,PRX2,PRXII,PTX1,TDPX1,TPX1,TSA

Catalog Number P11255-H07B
Organism Species Human
Host Baculovirus-Insect Cells
Synonyms HEL-S-2a,NKEF-B,NKEFB,PRP,PRX2,PRXII,PTX1,TDPX1,TPX1,TSA
Molecular Weight The recombinant human PRDX2 consists of 217 amino acids and predicts a molecular mass of 24 kDa. It migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions.
predicted N Met
SDS-PAGE
Purity > 92 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the human PRDX2 (P32119) (Met 1-Asn 198) was expressed, with a polyhistidine tag at the N-terminus.
Bio-activity Measured by its ability to reduce H2O2.
The specific activity is >300 pmoles/min/μg.
Research Area Signaling |Signal Transduction |Other Related Intracellular Topics |Cellular Senescence and Pathways in Aging |Apoptosis |Oxidative Stress |
Formulation Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% gly
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference
  • Cha M.-K., et al., 1995,  Biochem. Biophys. Res. Commun. 217:900-7.
  • Noh,D.Y. et al., 2001, Anticancer Res. 21 (3B): 2085-90.
  • Chevallet M., et al., 2003, J. Biol. Chem. 278:37146-53.
  • Schremmer,B. et al., 2007, Subcell Biochem. 44 :317-44.
  • Gauci S., et al., 2009, Anal. Chem. 81:4493-501.