Human Purine nucleoside phosphorylase / PNP Protein (His Tag)

NP,PRO1837,PUNP

Catalog Number	P12097-H08E
Organism Species	Human
Host	E. coli
Synonyms	NP,PRO1837,PUNP
Molecular Weight	The recombinant human PNP consisting of 299 amino acids and has a calculated molecular mass of 33.5 kDa as estimated in SDS-PAGE under reducing conditions.
predicted N	Met
SDS-PAGE
Purity	> 97 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human PNP (P00491) (Met 1-Ser 289) was fused with a polyhistide tag at the C-terminus.
Bio-activity
Research Area	Cancer \|Signal transduction \|Metabolism \|Pathways and Processes \|Vitamins / minerals
Formulation	Lyophilized from sterile PBS, 25% glycerol, pH 7.5 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	de Azevedo,W.F. et al., 2003, Biochem Biophys Res Commun. 312 (3): 767-72. Canduri,F. et al., 2005, Acta Crystallogr D Biol Crystallogr. 61 (Pt 7): 856-62. Perera,G.K. et al., 2005,Clin Exp Dermatol. 30 (1):27-9.