Human SLITRK4 / Slitrk4 Protein (His Tag)
DKFZp547M2010
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| Catalog Number | P13147-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | DKFZp547M2010 |
| Molecular Weight | The secreted recombinant human SLITRK4 comprises 609 amino acids and has a predicted molecular mass of 68.6 kDa. The apparent molecular mass of rhSLITRK4 is approximately 85 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| predicted N | Asp 19 |
| SDS-PAGE |  |
| Purity | > 92 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human SLITRK4 (Q8IW52) (Met 1-Pro 616) was fused with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Neuroscience |Neurology process |Growth and Development |Axon Guidance |SLITRK |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family.This protein is characterized as an integral membrane protein that has two leucine-rich repeat (LRR) domains and a carboxy-terminal domain that is partially similar to SLIT protein andTRK Neurotrophin There are six members in this family: SLITRK1, SLITRK2, SLITRK3, SLITRK4, SLITRK5, and SLITRK6. Their expression was detected mainly in the brain, but the expression profile of each SLITRK was unique. Each of these members is located in nervous system except for SLITRK6. SLITRK expression was also investigated in various types of brain tumor tissue. |
| Reference |